Bayesian optimal experimental design (BOED) selects experiments to maximize information gain about model parameters. However, in decision-critical settings, reducing parameter uncertainty does not necessarily improve downstream decisions, as only specific parameter directions relevant to the objective truly matter. We propose GoBOED, a goal-driven BOED framework that directly optimizes experimental designs for a specified decision-making objective. GoBOED combines an amortized variational posterior surrogate with a differentiable convex decision layer, enabling gradient-based design optimization that is fully decision-focused. We theoretically show that GoBOED gradients are insensitive to parameter directions irrelevant to the decision objective, providing a formal justification for why goal-driven design achieves equivalent decision quality over a wider set of experimental designs than information-gain maximization. Empirically, across source localization, epidemic management, and pharmacokinetic control, GoBOED identifies designs that better align with downstream decision objectives and reveals that near-optimal design windows are substantially wider than those predicted by goal-agnostic BOED approaches.

Typically,eachevaluationisexpensive in such applications, and we need to keep the number of evaluations to a minimum.

We propose MedBayes-Lite, a lightweight Bayesian enhancement for transformer-based clinical language models designed to produce reliable, uncertainty-aware predictions. Although transformers show strong potential for clinical decision support, they remain prone to overconfidence, especially in ambiguous medical cases where calibrated uncertainty is critical. MedBayes-Lite embeds uncertainty quantification directly into existing transformer pipelines without any retraining or architectural rewiring, adding no new trainable layers and keeping parameter overhead under 3 percent. The framework integrates three components: (i) Bayesian Embedding Calibration using Monte Carlo dropout for epistemic uncertainty, (ii) Uncertainty-Weighted Attention that marginalizes over token reliability, and (iii) Confidence-Guided Decision Shaping inspired by clinical risk minimization. Across biomedical QA and clinical prediction benchmarks (MedQA, PubMedQA, MIMIC-III), MedBayes-Lite consistently improves calibration and trustworthiness, reducing overconfidence by 32 to 48 percent. In simulated clinical settings, it can prevent up to 41 percent of diagnostic errors by flagging uncertain predictions for human review. These results demonstrate its effectiveness in enabling reliable uncertainty propagation and improving interpretability in medical AI systems.

The goal is to find the model, i.e. hyper-parameters, with the highest validation accuracy.

Multimodal learning integrates information from different modalities to enhance model performance, yet it often suffers from modality imbalance, where dominant modalities overshadow weaker ones during joint optimization. This paper reveals that such an imbalance not only occurs during representation learning but also manifests significantly at the decision layer. Experiments on audio-visual datasets (CREMAD and Kinetic-Sounds) show that even after extensive pretraining and balanced optimization, models still exhibit systematic bias toward certain modalities, such as audio. Further analysis demonstrates that this bias originates from intrinsic disparities in feature-space and decision-weight distributions rather than from optimization dynamics alone. We argue that aggregating uncalibrated modality outputs at the fusion stage leads to biased decision-layer weighting, hindering weaker modalities from contributing effectively. To address this, we propose that future multimodal systems should focus more on incorporate adaptive weight allocation mechanisms at the decision layer, enabling relative balanced according to the capabilities of each modality.

Although deep neural networks have demonstrated significant success due to their powerful expressiveness, most models struggle to meet practical requirements for uncertainty estimation. Concurrently, the entangled nature of deep neural networks leads to a multifaceted problem, where various localized explanation techniques reveal that multiple unrelated features influence the decisions, thereby undermining interpretability. To address these challenges, we develop a Bayesian N on-negative D ecision Layer ( BNDL), which reformulates deep neural networks as a conditional Bayesian non-negative factor analysis. By leveraging stochastic latent variables, the BNDL can model complex dependencies and provide robust uncertainty estimation. Moreover, the sparsity and non-negativity of the latent variables encourage the model to learn disentangled representations and decision layers, thereby improving interpretability. We also offer theoretical guarantees that BNDL can achieve effective disentangled learning. In addition, we developed a corresponding variational inference method utilizing a Weibull variational inference network to approximate the posterior distribution of the latent variables. Our experimental results demonstrate that with enhanced disentanglement capabilities, BNDL not only improves the model's accuracy but also provides reliable uncertainty estimation and improved interpretability. Over the last decade, deep neural networks (DNNs) have achieved significant success and have been widely applied across various research domains (LeCun et al., 2015). As these applications expand, quantifying uncertainty in predictions has gained importance, especially for AI safety (Amodei et al., 2016). A key goal of uncertainty estimation is to ensure that neural networks assign low confidence to test cases poorly represented by training data or prior knowledge (Gal & Ghahramani, 2016). One approach to this challenge is Bayesian neural networks, which treat model parameters as random variables.

Robotic systems are widely used to interact with humans or to perform critical tasks. As a result, it is imperative to provide guarantees about their behavior. Due to the modularity and complexity of robotic systems, their design and verification are often divided into several layers. However, some system properties can only be investigated by considering multiple layers simultaneously. We propose a cross-layer verification method to verify the expected properties of concrete robotic systems. Our method verifies one layer using abstractions of other layers. We propose two approaches: refining the models of the abstract layers and refining the property under verification. A combination of these two approaches seems to be the most promising to ensure model genericity and to avoid the state-space explosion problem.

While deep neural networks (DNNs) based personalized federated learning (PFL) is demanding for addressing data heterogeneity and shows promising performance, existing methods for federated learning (FL) suffer from efficient systematic uncertainty quantification. The Bayesian DNNs-based PFL is usually questioned of either over-simplified model structures or high computational and memory costs. In this paper, we introduce FedSI, a novel Bayesian DNNs-based subnetwork inference PFL framework. FedSI is simple and scalable by leveraging Bayesian methods to incorporate systematic uncertainties effectively. It implements a client-specific subnetwork inference mechanism, selects network parameters with large variance to be inferred through posterior distributions, and fixes the rest as deterministic ones. FedSI achieves fast and scalable inference while preserving the systematic uncertainties to the fullest extent. Extensive experiments on three different benchmark datasets demonstrate that FedSI outperforms existing Bayesian and non-Bayesian FL baselines in heterogeneous FL scenarios.

Recognizing facial action units (AUs) from spontaneous facial expressions is still a challenging problem. Most recently, CNNs have shown promise on facial AU recognition. However, the learned CNNs are often overfitted and do not generalize well to unseen subjects due to limited AU-coded training images. We proposed a novel Incremental Boosting CNN (IB-CNN) to integrate boosting into the CNN via an incremental boosting layer that selects discriminative neurons from the lower layer and is incrementally updated on successive mini-batches. In addition, a novel loss function that accounts for errors from both the incremental boosted classifier and individual weak classifiers was proposed to fine-tune the IB-CNN. Experimental results on four benchmark AU databases have demonstrated that the IB-CNN yields significant improvement over the traditional CNN and the boosting CNN without incremental learning, as well as outperforming the state-of-the-art CNN-based methods in AU recognition. The improvement is more impressive for the AUs that have the lowest frequencies in the databases.

This is a summary paper of a use case of a Robotdog dedicated to guide visually impaired people in complex environment like a smart intersection. In such scenarios, the Robotdog has to autonomously decide whether it is safe to cross the intersection or not in order to further guide the human. We leverage data sharing and collaboration between the Robotdog and other autonomous systems operating in the same environment. We propose a system architecture for autonomous systems through a separation of a collaborative decision layer, to enable collective decision making processes, where data about the environment, relevant to the Robotdog decision, together with evidences for trustworthiness about other systems and the environment are shared.